1. Metabolic Enzyme/Protease
  2. Factor Xa
  3. Asundexian

Asundexian (Synonyms: BAY-2433334)

Cat. No.: HY-137431
Handling Instructions

Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM.

For research use only. We do not sell to patients.

Asundexian Chemical Structure

Asundexian Chemical Structure

CAS No. : 2064121-65-7

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Description

Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1].

In Vivo

Asundexian displays potent anticoagulant activity in vitro in human and rabbit plasma and antithrombotic efficacy in vivo in a rabbit arterial thrombosis model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

592.93

Formula

C₂₆H₂₁ClF₄N₆O₄

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Asundexian
Cat. No.:
HY-137431
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