2068818-75-5
2068818-75-5
Chemical Structure
NBC19
- CAS No.: 2068818-75-5
- Formula:C24H26BCl3N2O2
- Molecular Weight:491.65
IUPAC Name: 1-(6-(cyclohexylamino)-2,2-diphenyl-4-(trichloromethyl)-2,3-dihydro-1l3,3,2l4-oxazaborinin-5-yl)ethan-1-one
InChIKey: XLUPBOKHLVUFLX-UHFFFAOYSA-N
SMILES: O=C(C)C1=C(C(Cl)(Cl)Cl)N[B-](C2=CC=CC=C2)(C3=CC=CC=C3)[O+]=C1NC4CCCCC4
Biological Activity: NBC19 is an NLRP3 inflammasome inhibitor with an IC50 of 60 nM in differentiated THP1 cells. NBC19 inhibits nigericin- and ATP-induced IL-1β release with IC50s of 80 nM and 850 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NBC19 | 99.22% | NBC19 is an NLRP3 inflammasome inhibitor with an IC50 of 60 nM in differentiated THP1 cells. NBC19 inhibits nigericin- and ATP-induced IL-1β release with IC50s of 80 nM and 850 nM, respectively. | ||||||||||||||||||||
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References
Keywords
