2072857-15-7
2072857-15-7
Chemical Structure
JDS364
- CAS No.: 2072857-15-7
- Formula:C19H20N4O2
- Molecular Weight:336.39
InChIKey: QBVIYHCPRAHKBD-LPYMAVHISA-N
SMILES: OC1=CC=C(CCCCNC2=CC=NC3=CC=CC=C23)N=C1/C=N/O
Biological Activity: JDS364 is a blood-brain barrier-permeable human acetylcholinesterase (hAChE) reactivator with an IC50 of 8.6 μM. JDS364 achieves rapid systemic exposure in mice and acts as a protective agent when used in combination with Atropine (HY-B1205). JDS364 can be used in studies on organophosphate nerve agent poisoning and organophosphate pesticide poisoning[1].
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JDS364 | JDS364 is a blood-brain barrier-permeable human acetylcholinesterase (hAChE) reactivator with an IC50 of 8.6 μM. JDS364 achieves rapid systemic exposure in mice and acts as a protective agent when used in combination with Atropine (HY-B1205). JDS364 can be used in studies on organophosphate nerve agent poisoning and organophosphate pesticide poisoning. | |||||||||||||||||||||
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References
Keywords
