209984-68-9
Chemical Structure
LY900009
- CAS No.: 209984-68-9
- Formula:C23H27N3O4
- Molecular Weight:409.48
IUPAC Name: (S)-2-hydroxy-3-methyl-N-((S)-1-(((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)amino)-1-oxopropan-2-yl)butanamide
InChIKey: JURYTIUJMYPBNN-GKCIPKSASA-N
SMILES: CC(C)[C@H](O)C(N[C@@H](C)C(N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C)C1=O)=O)=O
Biological Activity: LY900009 is a potent and orally active, First-in-class inhibitor of Notch signaling via selective inhibition of the γ-secretase protein (GSI). LY900009 inhibits Notch signalling in tumor cell lines and endothelial cells (IC50=0.005-20 nM). LY900009 can be used for advanced cancer research[1].
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LY900009 | 98.40% | LY900009 is a potent and orally active, First-in-class inhibitor of Notch signaling via selective inhibition of the γ-secretase protein (GSI). LY900009 inhibits Notch signalling in tumor cell lines and endothelial cells (IC50=0.005-20 nM). LY900009 can be used for advanced cancer research. | ||||||||||||||||||||
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Keywords
