2102347-47-5
Chemical Structure
LFHP-1c
- CAS No.: 2102347-47-5
- Formula:C55H64N6O4
- Molecular Weight:873.13
IUPAC Name: 1-(2-((8-(4'-((1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxamido)octyl)carbamoyl)phenyl)pentyl acetate
InChIKey: OITTXMIOSJEXLY-UHFFFAOYSA-N
SMILES: O=C(C)OC(CCCC)C1=C(C(NCCCCCCCCNC(C2=C(C3=CC=C(CN4C5=CC(C6=NC7=C(N6C)C=CC=C7)=CC(C)=C5N=C4CCC)C=C3)C=CC=C2)=O)=O)C=CC=C1
Biological Activity: LFHP-1c is an PGAM5 inhibitor with neuroprotective activity in brain ischemic stroke. LFHP-1c protects blood-brain barrier integrity from ischemia-induced injury. LFHP-1c binds to endothelial PGAM5 to inhibit the activity of PGAM5 phosphatase and the interaction of PGAM5 with NRF2. LFHP-1c exhibits in vitro and in vivo protection[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LFHP-1c | 98.01% | LFHP-1c is an PGAM5 inhibitor with neuroprotective activity in brain ischemic stroke. LFHP-1c protects blood-brain barrier integrity from ischemia-induced injury. LFHP-1c binds to endothelial PGAM5 to inhibit the activity of PGAM5 phosphatase and the interaction of PGAM5 with NRF2. LFHP-1c exhibits in vitro and in vivo protection. | ||||||||||||||||||||
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-
Similarity Score 0.67
HY-163132DDABT1 -
Similarity Score 0.65
HY-W715597Telmisartan impurity 11 -
Similarity Score 0.64
HY-146480PPARγ agonist 5 -
Similarity Score 0.64
HY-Z8777Telmisartan impurity 18 -
Similarity Score 0.64
HY-131316Telmisartan impurity 19 -
Similarity Score 0.63
HY-13955Telmisartan -
Similarity Score 0.62
HY-137959Telmisartan acyl-β-D-glucuronide -
Similarity Score 0.60
HY-W719097Telmisartan impurity 15 -
Similarity Score 0.59
HY-W437299Telmisartan impurity 10 -
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