2117631-52-2
Chemical Structure
HCM-01
- CAS No.: 2117631-52-2
- Formula:C37H36N6O6
- Molecular Weight:660.72
InChIKey: JBMCGEGZCFDRSS-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N=C(C)C(C(NCCC2=CNC3=C2C=C(OC)C=C3)=O)=C1C4=C([N+]([O-])=O)C=CC=C4)NCCC5=CNC6=C5C=C(OC)C=C6
Biological Activity: HCM-01 is an Excitatory amino acid transporter 2 (EAAT2) activator with oral effectiveness and blood-brain barrier penetration.HCM-01 binds to the allosteric site of EAAT2, increases EAAT2 expression in astrocytes, enhances glutamate-handling capacity, and modulates glutamate homeostasis.HCM-01 acts as an antioxidant, improves oxidative/antioxidative balance and increases total antioxidant capacity. HCM-01 can be used for the research of Alzheimer's disease[1].
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HCM-01 | HCM-01 is an Excitatory amino acid transporter 2 (EAAT2) activator with oral effectiveness and blood-brain barrier penetration.HCM-01 binds to the allosteric site of EAAT2, increases EAAT2 expression in astrocytes, enhances glutamate-handling capacity, and modulates glutamate homeostasis.HCM-01 acts as an antioxidant, improves oxidative/antioxidative balance and increases total antioxidant capacity. HCM-01 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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Keywords
