212571-56-7
212571-56-7
Chemical Structure
TAK-070 Free base
- CAS No.: 212571-56-7
- Formula:C27H31NO
- Molecular Weight:385.54
IUPAC Name: (R)-2-(6-([1,1'-biphenyl]-4-ylmethoxy)-1,2,3,4-tetrahydronaphthalen-2-yl)-N,N-dimethylethan-1-amine
InChIKey: SETMAZMOXYOEJA-NRFANRHFSA-N
SMILES: CN(CC[C@H]1CC2=C(CC1)C=C(C=C2)OCC3=CC=C(C=C3)C4=CC=CC=C4)C
Biological Activity: TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model[1].
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TAK-070 Free base | TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model. | |||||||||||||||||||||
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References
Keywords
