2. Neuronal Signaling
  3. Beta-secretase
  4. TAK-070 Free base

TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model.

For research use only. We do not sell to patients.

TAK-070 Free base Chemical Structure

TAK-070 Free base Chemical Structure

CAS No. : 212571-56-7

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TAK-070 Free base Related Antibodies

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Description

TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model[1].

IC50 & Target

3.15 μM (BACE1)[1].
Molecular Weight

385.54

Formula

C27H31NO
CAS No.
SMILES

CN(CC[C@H]1CC2=C(CC1)C=C(C=C2)OCC3=CC=C(C=C3)C4=CC=CC=C4)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TAK-070 Free base Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAK-070212571-56-7TAK070TAK 070Beta-secretaseBACEβ-Secretaseorally activeAlzheimer’sAD modelsoluble AβInhibitorinhibitorinhibit

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