country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-114234A

Copy Link Print Information

TAK-070 Free base

TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC₅₀: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 212571-56-7
화학식: C₂₇H₃₁NO
분자량:385.54

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

TAK-070 Free base Chemical Structure

CAS No.: 212571-56-7

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

BACE1

All Beta-secretase Isoforms :

BACE1
BACE2

Chemical Information

CAS No. 212571-56-7
분자량 385.54
화학식 C₂₇H₃₁NO
SMILES

CN(CC[C@H]1CC2=C(CC1)C=C(C=C2)OCC3=CC=C(C=C3)C4=CC=CC=C4)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fukumoto H, et al. A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease. J Neurosci. 2010 Aug 18;30(33):11157-66. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

TAK-070 Free base

BCA

Tenuifolin

Eslicarbazepine

β-Secretase Inhibitor IV

Verubecestat TFA

(1α,1'S,4β)-Lanabecestat

Eslicarbazepine (Standard)

Tenuifolin (Standard)

β-Secretase Inhibitor IV (Standard)

LY2886721 hydrochloride

Deoxyneocryptotanshinone

(1α,1'S,4β)-Lanabecestat (Standard)

All Beta-secretase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

TAK-070 Free base

BCA

Tenuifolin

Eslicarbazepine

β-Secretase Inhibitor IV

Verubecestat TFA

(1α,1'S,4β)-Lanabecestat

Eslicarbazepine (Standard)

Tenuifolin (Standard)

β-Secretase Inhibitor IV (Standard)

LY2886721 hydrochloride

Deoxyneocryptotanshinone

(1α,1'S,4β)-Lanabecestat (Standard)

All Beta-secretase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

TAK-070 Free base Related Classifications

HY-114234A Related Classifications