212631-61-3
212631-61-3
Chemical Structure
PD 198306
- CAS No.: 212631-61-3
- Formula:C18H16F3IN2O2
- Molecular Weight:476.23
IUPAC Name: N-(cyclopropylmethoxy)-3,4,5-trifluoro-2-((4-iodo-2-methylphenyl)amino)benzamide
InChIKey: UHAXDAKQGVISBZ-UHFFFAOYSA-N
SMILES: O=C(NOCC1CC1)C(C=C(F)C(F)=C2F)=C2NC3=C(C=C(I)C=C3)C
Biological Activity: PD 198306 is a selective MAPK/ERK-kinase (MEK) inhibitor. PD 198306 results in an observable reduction in the Streptozocin induced increase in the level of active ERK1 and 2. Antihyperalgesic effects[1].
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PD 198306 | 99.75% | PD 198306 is a selective MAPK/ERK-kinase (MEK) inhibitor. PD 198306 results in an observable reduction in the Streptozocin induced increase in the level of active ERK1 and 2. Antihyperalgesic effects. | ||||||||||||||||||||
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PD 198306 (Standard) | PD 198306 (Standard) is the analytical standard of PD 198306 (HY-107620). This product is intended for research and analytical applications. PD 198306 is a selective MAPK/ERK-Kinase (MEK) inhibitor. PD 198306 results in an observable reduction in the Streptozocin induced increase in the level of active ERK1 and 2. Antihyperalgesic effects. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.74
HY-10174PD184161 -
Similarity Score 0.74
HY-50295RCI-1040 (Standard) -
Similarity Score 0.71
HY-118626PD-254552 -
Similarity Score 0.65
HY-131295PD0325901-O-C2-dioxolane -
Similarity Score 0.65
HY-10254RMirdametinib (Standard) -
Similarity Score 0.64
HY-12062PD318088 -
Similarity Score 0.61
HY-168288MEK ligand-2 -
Similarity Score 0.61
HY-10508(R)-PD 0325901CL -
Similarity Score 0.60
HY-14719RRO4987655 (Standard) -
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