2133010-38-3
2133010-38-3
Chemical Structure
SMW139
- CAS No.: 2133010-38-3
- Formula:C19H21ClF3NO2
- Molecular Weight:387.82
InChIKey: DWSQAAMUNCFYTG-BGQCMDAUSA-N
SMILES: O=C(C1=CC(OC)=CC=C1Cl)NCC(C[C@]2(C3)F)(C[C@@]43F)C[C@](C4)(C2)F
Biological Activity: SMW139 is a selective allosteric antagonist of P2X7 receptor, with a Ki value of 32 nM for human P2X7R. The half-life of SMW139 in rat liver microsomes is 47 minutes. SMW139 can be used for inflammation, Alzheimer’s disease, multiple sclerosis study[1].
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SMW139 | SMW139 is a selective allosteric antagonist of P2X7 receptor, with a Ki value of 32 nM for human P2X7R. The half-life of SMW139 in rat liver microsomes is 47 minutes. SMW139 can be used for inflammation, Alzheimer’s disease, multiple sclerosis study. | |||||||||||||||||||||
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