2143072-85-7
2143072-85-7
Chemical Structure
RAGE 229
- CAS. Nr.: 2143072-85-7
- Formula:C23H22N4O2
- Molecular Weight:386.45
IUPAC Name: N-(4-(7-cyano-4-(morpholinomethyl)quinolin-2-yl)phenyl)acetamide
InChIKey: VDYYVNHJRNDKDO-UHFFFAOYSA-N
SMILES: CC(NC1=CC=C(C2=NC3=CC(C#N)=CC=C3C(CN4CCOCC4)=C2)C=C1)=O
Biological Activity: RAGE 229 is an orally active ctRAGE-DIAPH1 inhibitor. RAGE 229 can inhibit the intracellular RAGE signaling by inhibiting the interaction between the cytoplasmic tail of RAGE(ctRAGE) and Diaphanous-1(DIAPH1)[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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RAGE 229 | 99.89% | RAGE 229 is an orally active ctRAGE-DIAPH1 inhibitor. RAGE 229 can inhibit the intracellular RAGE signaling by inhibiting the interaction between the cytoplasmic tail of RAGE(ctRAGE) and Diaphanous-1(DIAPH1). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-178926RAGE406R -
Similarity Score 0.58
HY-117684Cabamiquine -
Similarity Score 0.55
HY-13862AZD1080 -
Similarity Score 0.54
HY-156818TNIK-IN-7 -
Similarity Score 0.53
HY-117684ACabamiquine succinate -
Similarity Score 0.53
HY-146727JAK3-IN-11 -
Similarity Score 0.52
HY-10961Momelotinib -
Similarity Score 0.52
HY-134923CA77.1 -
Similarity Score 0.52
HY-178335SGC-CK1γ-1 -
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