SGC-CK1γ-1
Based on 1 Customer Validation
SGC-CK1γ-1 is a potent and selective probe for the CK1γ subfamily. SGC-CK1γ-1 can inhibit LRP6 phosphorylation levels. SGC-CK1γ-1 can selectively inhibit the CK1γ kinases in living cells and inhibit both WNT signaling and human cytomegalovirus (CMV) replication. SGC-CK1γ-1 can be used for the research of infection.
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 3125107-49-2
- Formula: C18H16ClN5O
- Molecular Weight:353.81
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
SGC-CK1γ-1 (5-10 μM, 2h) inhibits LRP6 phosphorylation levels in HEK293 cells[1].
SGC-CK1γ-1 (10 μM, 24-48 h) does not impact cell viability in HEK293 cells[1].
SGC-CK1γ-1 (1-10 μM) elicits anti-HCMV replication effects in HFF cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3125107-49-2
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Appearance Solid
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Molecular Weight 353.81
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Formula C18H16ClN5O
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Color White to light yellow
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SMILES
N#CC1=CC=C2C(N=C(NC3=CC=C(N4CCOCC4)C(Cl)=C3)N2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)