2144777-92-2
Chemical Structure
Azido-PEG5-CH2CO2-PFP
- CAS No.: 2144777-92-2
- Formula:C18H22F5N3O7
- Molecular Weight:487.38
IUPAC Name: perfluorophenyl 17-azido-3,6,9,12,15-pentaoxaheptadecanoate
InChIKey: NITGTHWASXRERB-UHFFFAOYSA-N
SMILES: O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)COCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azido-PEG5-CH2CO2-PFP | Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
