2163060-83-9
2163060-83-9
Chemical Structure
WY-135
- CAS No.: 2163060-83-9
- Formula:C28H34ClN9O3S
- Molecular Weight:612.15
IUPAC Name: 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)phenyl)pyrimidine-2,4-diamine
InChIKey: MYBIYOGYGXIDJG-UHFFFAOYSA-N
SMILES: CC(C)S(C1=C(NC2=NC(NC3=C(OC)C=C(N4C=C(CN5CCN(C)CC5)N=N4)C=C3)=NC=C2Cl)C=CC=C1)(=O)=O
Biological Activity: WY-135 is an ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.
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WY-135 | WY-135 is an ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor. | |||||||||||||||||||||
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Keywords
