2170653-14-0
2170653-14-0
Chemical Structure
PSMA binder-1
- CAS No.: 2170653-14-0
- Formula:C21H26N4O8
- Molecular Weight:462.45
InChIKey: SPDPBCMAHFFQAM-HOTGVXAUSA-N
SMILES: C#CC1=CC=CC(NC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=C1
Biological Activity: PSMA binder-1 is a ligand for PSMA and can be used to synthesize PSMA targeting molecule, such as Ac-PSMA-trillium[1][2].
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PSMA binder-1 | 98.88% | PSMA binder-1 is a ligand for PSMA and can be used to synthesize PSMA targeting molecule, such as Ac-PSMA-trillium. | ||||||||||||||||||||
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References
- [1]. Sun M, et al. Prostate-Specific Membrane Antigen (PSMA)-Targeted Radionuclide Therapies for Prostate Cancer. Curr Oncol Rep. 2021 Mar 29;23(5):59. [Content Brief]
- [2]. Zitzmann-Kolbe S, et al., Preclinical evaluation of an actinium-225 labeled PSMA-targeting small molecule (225Ac-PSMA-Trillium (BAY 3563254)) for the treatment of metastatic castration resistant prostate cancer (mCRPC)[J]. Cancer Research, 2024, 84(6_Supplement): 6033-6033.
