218162-38-0
Chemical Structure
RPR-200765A methanesulfonate
- CAS No.: 218162-38-0
- Formula:C25H29FN4O7S
- Molecular Weight:548.58
IUPAC Name: ((2s,5s)-2-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)-5-methyl-1,3-dioxan-5-yl)(morpholino)methanone methanesulfonate
InChIKey: HYXPWOSDWIYCSH-PEUGIQGRSA-N
SMILES: O=C([C@@]1(C)CO[C@@H](C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)OC1)N5CCOCC5.CS(=O)(O)=O
Biological Activity: RPR-200765A methanesulfonate is an orally active p38 MAPK inhibitor with an IC50 of 0.050 μM. RPR-200765A methanesulfonate shows weak activity against Lck, and exhibits no significant activity against ERK, ZAP70 or SYK. It inhibits the production of TNFα and can be used in the research of inflammatory diseases[1].
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RPR-200765A methanesulfonate | RPR-200765A methanesulfonate is an orally active p38 MAPK inhibitor with an IC50 of 0.050 μM. RPR-200765A methanesulfonate shows weak activity against Lck, and exhibits no significant activity against ERK, ZAP70 or SYK. It inhibits the production of TNFα and can be used in the research of inflammatory diseases. | |||||||||||||||||||||
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Keywords
