2216764-29-1
2216764-29-1
Chemical Structure
CD73-IN-4
- CAS No.: 2216764-29-1
- Formula:C16H23ClN5O7P
- Molecular Weight:463.81
IUPAC Name: ((((2R,3S,4R,5R)-5-(6-chloro-4-(cyclopentylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)phosphonic acid
InChIKey: IVHVIBKVJIZKOC-RTWAVKEYSA-N
SMILES: ClC1=NC(N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COCP(O)(O)=O)N=C3)=C3C(NC4CCCC4)=N1
Biological Activity: CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CD73-IN-4 | 99.35% | CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.82
HY-136978OP-5244 -
Similarity Score 0.79
HY-131435CD73-IN-2 -
Similarity Score 0.73
HY-160696ORIC-533 -
Similarity Score 0.60
HY-103185RCCPA (Standard) -
Similarity Score 0.58
![6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152410.gif)
HY-1524106-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine -
Similarity Score 0.56
![2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152408.gif)
HY-1524082-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine -
Similarity Score 0.56
![1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152828.gif)
HY-1528281-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine -
Similarity Score 0.55
HY-1524602-Chloro-N6-cyclopentyl-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine -
Similarity Score 0.55
HY-106007Trabodenoson -
Explore the MedChemAI to find more analogs
![6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152410.gif)
![2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152408.gif)
![1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152828.gif)
