2248702-80-7
2248702-80-7
Chemical Structure
TDP1 Inhibitor-1
- CAS No.: 2248702-80-7
- Formula:C26H26N2O5
- Molecular Weight:446.50
IUPAC Name: 2,3-dimethoxy-13-(2-(pyrrolidin-1-yl)ethoxy)-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine
InChIKey: AXNFOXAWCCNLFG-UHFFFAOYSA-N
SMILES: COC1=C(OC)C=C(C(OCCN2CCCC2)=NC3=C4C=CC5=CC6=C(OCO6)C=C35)C4=C1
Biological Activity: TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM. TDP1 Inhibitor-1 shows cytotoxicity against multiple cancer cells. TDP1 Inhibitor-1 can be used for the research of cancer, such as breast cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TDP1 Inhibitor-1 | 98.33% | TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM. TDP1 Inhibitor-1 shows cytotoxicity against multiple cancer cells. TDP1 Inhibitor-1 can be used for the research of cancer, such as breast cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.79
HY-181080TOP1/TDP1-IN-1 -
Similarity Score 0.62
HY-W676876Oxynitidine -
Similarity Score 0.61
HY-N0498Nitidine chloride -
Similarity Score 0.60
HY-N7505Norchelerythrine -
Similarity Score 0.57
HY-N3700Decarine -
Similarity Score 0.56
HY-12048RChelerythrine chloride (Standard) -
Similarity Score 0.56
HY-N2359AChelerythrine hydroxide -
Similarity Score 0.56
HY-118942Topovale -
Similarity Score 0.56
HY-183334TDP1-IN-5 -
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