2260631-91-0
Chemical Structure
RORγ agonist 1
- CAS No.: 2260631-91-0
- Formula:C29H27ClF4N2O4S
- Molecular Weight:611.05
IUPAC Name: (R)-2-(4-chloro-2-(trifluoromethyl)benzyl)-N-(1-(4-(ethylsulfonyl)phenyl)-2-hydroxyethyl)-1-(2-fluoroethyl)-1H-indole-5-carboxamide
InChIKey: QZQCXURNZJAFEH-SANMLTNESA-N
SMILES: FCCN1C2=CC=C(C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CO)=O)C=C2C=C1CC4=C(C=C(C=C4)Cl)C(F)(F)F
Biological Activity: RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC50 = 21 nM) with antitumor activity.
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RORγ agonist 1 | RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC50 = 21 nM) with antitumor activity. | |||||||||||||||||||||
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Keywords