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Cat. No.: HY-132900

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RORγ agonist 1

RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC₅₀ = 21 nM) with antitumor activity.

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CAS No.: 2260631-91-0
Formule: C₂₉H₂₇ClF₄N₂O₄S
Masse moléculaire:611.05

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

RORγ agonist 1 Chemical Structure

CAS No.: 2260631-91-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC₅₀ = 21 nM) with antitumor activity.

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Chemical Information

CAS No. 2260631-91-0
Masse moléculaire 611.05
Formule C₂₉H₂₇ClF₄N₂O₄S
SMILES

FCCN1C2=CC=C(C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CO)=O)C=C2C=C1CC4=C(C=C(C=C4)Cl)C(F)(F)F
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Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lu B, et al. Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity. J Med Chem. 2021 Oct 28;64(20):14983-14996. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RORγ agonist 1

Voir tous les produits spécifiques à Isoform ROR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RORγ agonist 1 Related Classifications

HY-132900 Related Classifications