2260670-13-9
2260670-13-9
Chemical Structure
C18 Glucosyl(ß) ceramide-d5
- CAS No.: 2260670-13-9
- Formula:C42H76D5NO8
- Molecular Weight:733.13
IUPAC Name: ammonium (2S,3R,E)-3-hydroxy-2-pentadecanamidooctadec-4-en-1-yl-16,16,17,17,18,18,18-d7 hydrogen phosphate
InChIKey: YMYQEDCYNANIPI-PFHCAOQOSA-N
SMILES: [2H]C([2H])([2H])C([2H])([2H])CCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCCCCCC)=O)CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO
Biological Activity: C18 Glucosyl(ß) ceramide-d5 is deuterium labeled C18 Glucosyl(ß) ceramide.
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C18 Glucosyl(ß) ceramide-d5 | 99% | C18 Glucosyl(ß) ceramide-d5 is deuterium labeled C18 Glucosyl(ß) ceramide. | ||||||||||||||||||||
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GlcCer (d18:1/18:0) | 99.93% | GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a glycosphingolipids that activates the Wnt/β-catenin pathway by targeting LRP6. GlcCer (d18:1/18:0) drives EMT, migration, invasion and GBA1-mediated liver cancer metastasis. GlcCer (d18:1/18:0) accumulates to impair lysosomal function and induce toxic α-synuclein aggregation. GlcCer (d18:1/18:0) supports growth, sporulation, germination and virulence in Penicillium digitatum. GlcCer (d18:1/18:0) is reduced in demyelinated mouse corpus callosum. GlcCer (d18:1/18:0) can be used for the research of liver cancer, synucleinopathies, fungal, Parkinson’s disease and Gaucher disease. | ||||||||||||||||||||
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