23094-69-1
Chemical Structure
Corilagin
Synonym(s): NP-004255
- CAS No.: 23094-69-1
- Formula:C27H22O18
- Molecular Weight:634.45
IUPAC Name: (52R,53S,54R,55S,56S)-14,15,16,24,25,26,53,55-octahydroxy-3,8-dioxo-53,54,55,56-tetrahydro-52H-4,7-dioxa-5(4,2)-pyrana-1,2(1,2)-dibenzenacyclooctaphane-56-yl 3,4,5-trihydroxybenzoate
InChIKey: TUSDEZXZIZRFGC-WADXKLOKSA-N
SMILES: O[C@@H]1[C@@H](COC(C2=C(C3=C(O)C(O)=C(O)C=C34)C(O)=C(O)C(O)=C2)=O)O[C@@H](OC(C5=CC(O)=C(O)C(O)=C5)=O)[C@H](O)[C@H]1OC4=O
Biological Activity: Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Corilagin | 99.96% | Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues. | ||||||||||||||||||||
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Corilagin (Standard) | 99.98% | Corilagin (Standard) is the analytical standard of Corilagin. This product is intended for research and analytical applications. Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues. | ||||||||||||||||||||
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References
- [1]. Li X, et al. Corilagin, a promising medicinal herbal agent. Biomed Pharmacother. 2018 Mar;99:43-50. [Content Brief]
- [2]. Xu J, et al. Corilagin induces apoptosis, autophagy and ROS generation in gastric cancer cells in vitro. Int J Mol Med. 2019 Feb;43(2):967-979. [Content Brief]
- [3]. Jia L, et al. A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways. BMC Complement Altern Med. 2013 Feb 15;13:33. [Content Brief]
