2349374-37-2
Chemical Structure
15-LOX-1 inhibitor 1
- CAS No.: 2349374-37-2
- Formula:C22H21ClN2O4
- Molecular Weight:412.87
IUPAC Name: ethyl (E)-6-chloro-3-(3-((2-methoxybenzyl)amino)-3-oxoprop-1-en-1-yl)-1H-indole-2-carboxylate
InChIKey: BRMZRDPEXXAZRV-ZHACJKMWSA-N
SMILES: O=C(C(N1)=C(/C=C/C(NCC2=CC=CC=C2OC)=O)C3=C1C=C(Cl)C=C3)OCC
Biological Activity: 15-LOX-1 inhibitor 1 is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC50 value of 0.19 μM. 15-LOX-1 inhibitor 1 protects macrophages from lipopolysaccharide-induced cytotoxicity. 15-LOX-1 inhibitor 1 inhibits NO formation and lipid peroxidation[1].
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15-LOX-1 inhibitor 1 | 98.81% | 15-LOX-1 inhibitor 1 is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC50 value of 0.19 μM. 15-LOX-1 inhibitor 1 protects macrophages from lipopolysaccharide-induced cytotoxicity. 15-LOX-1 inhibitor 1 inhibits NO formation and lipid peroxidation. | ||||||||||||||||||||
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Keywords