2351886-00-3
2351886-00-3
Chemical Structure
SPL-410
- CAS 番号: 2351886-00-3
- Formula:C24H31F3N2O4S
- Molecular Weight:500.57
IUPAC Name: N-((2S,3S)-3-amino-2-hydroxy-3-(4-(trifluoromethoxy)phenyl)propyl)-4-(tert-butyl)-N-cyclobutylbenzenesulfonamide
InChIKey: KEEHEUGOPCFXAV-VXKWHMMOSA-N
SMILES: N[C@H]([C@@H](O)CN(C1CCC1)S(C2=CC=C(C(C)(C)C)C=C2)(=O)=O)C3=CC=C(OC(F)(F)F)C=C3
Biological Activity: SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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SPL-410 | 98.53% | SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.52
HY-174998HIV-1 protease-IN-15 -
Similarity Score 0.51
HY-155690HIV-1 protease-IN-11 -
Similarity Score 0.49
HY-124669RTC-30 -
Similarity Score 0.49
HY-103406APNU-177864 hydrochloride -
Similarity Score 0.49
HY-149936HIV-1 protease-IN-8 -
Similarity Score 0.49
HY-155691HIV-1 protease-IN-12 -
Similarity Score 0.49
HY-103406PNU-177864 -
Similarity Score 0.49
HY-131443TRC-766 -
Similarity Score 0.48
HY-147650HIV-1 protease-IN-5 -
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