2353496-84-9
2353496-84-9
Chemical Structure
Thalidomide-C2-amido-C2-COOH
- CAS No.: 2353496-84-9
- Formula:C19H20N4O7
- Molecular Weight:416.38
IUPAC Name: 4-((2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-4-oxobutanoic acid
InChIKey: NESMQJNZCMFMPK-UHFFFAOYSA-N
SMILES: O=C(O)CCC(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O
Biological Activity: Thalidomide-C2-amido-C2-COOH contains a CRBN ligand and a linker for recruiting E3 ubiquitin ligases. Thalidomide-C2-amido-C2-COOH can be used to design and synthesize PROTAC CDK2/9 Degrader-1 (HY-130709). PROTAC CDK2/9 Degrader-1 is applicable to prostate cancer-related research[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Thalidomide-C2-amido-C2-COOH | 98.45% | Thalidomide-C2-amido-C2-COOH contains a CRBN ligand and a linker for recruiting E3 ubiquitin ligases. Thalidomide-C2-amido-C2-COOH can be used to design and synthesize PROTAC CDK2/9 Degrader-1 (HY-130709). PROTAC CDK2/9 Degrader-1 is applicable to prostate cancer-related research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.88
HY-174863Pomalidomide-C2-PEG-NHCO-C2-COOH -
Similarity Score 0.86
HY-164391Pomalidomide-C2-amide-C4-Br -
Similarity Score 0.84
HY-131875Pomalidomide 4'-alkylC3-acid -
Similarity Score 0.83
HY-150006Pomalidomide-C2-acid -
Similarity Score 0.83
HY-131886Pomalidomide 4'-alkylC4-acid -
Similarity Score 0.83
HY-168544Succinic acid-Pomalidomide -
Similarity Score 0.83
HY-137531Pomalidomide-PEG1-C2-COOH -
Similarity Score 0.82
HY-130737Pomalidomide 4'-alkylC5-acid -
Similarity Score 0.82
HY-138849Thalidomide-NH-amido-C2-NH2 -
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