2353496-84-9
Chemical Structure
Thalidomide-C2-amido-C2-COOH
- CAS No.: 2353496-84-9
- Formula:C19H20N4O7
- Molecular Weight:416.38
IUPAC Name: 4-((2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-4-oxobutanoic acid
InChIKey: NESMQJNZCMFMPK-UHFFFAOYSA-N
SMILES: O=C(O)CCC(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O
Biological Activity: Thalidomide-C2-amido-C2-COOH contains a CRBN ligand and a linker for recruiting E3 ubiquitin ligases. Thalidomide-C2-amido-C2-COOH can be used to design and synthesize PROTAC CDK2/9 Degrader-1 (HY-130709). PROTAC CDK2/9 Degrader-1 is applicable to prostate cancer-related research[1].
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Thalidomide-C2-amido-C2-COOH | 98.45% | Thalidomide-C2-amido-C2-COOH contains a CRBN ligand and a linker for recruiting E3 ubiquitin ligases. Thalidomide-C2-amido-C2-COOH can be used to design and synthesize PROTAC CDK2/9 Degrader-1 (HY-130709). PROTAC CDK2/9 Degrader-1 is applicable to prostate cancer-related research. | ||||||||||||||||||||
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Keywords
