2363756-50-5
Chemical Structure
Azido-PEG12-NHS ester
- CAS No.: 2363756-50-5
- Formula:C31H56N4O16
- Molecular Weight:740.79
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oate
InChIKey: JSNJRDFOCXNHTB-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azido-PEG12-NHS ester | 98.0% | Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Similarity Score 0.92
HY-140759Azido-PEG10-NHS ester -
Similarity Score 0.92
HY-141107m-PEG13-NHS ester -
Similarity Score 0.90
HY-141106m-PEG12-NHS ester -
Similarity Score 0.89
HY-141097Acid-PEG13-NHS ester -
Similarity Score 0.89
HY-140758Azido-PEG9-NHS ester -
Similarity Score 0.88
HY-140761Azido-PEG16-NHS ester -
Similarity Score 0.87
HY-141105m-PEG11-NHS ester -
Similarity Score 0.85
HY-W591384Boc-NH-PEG12-NHSester -
Similarity Score 0.85
HY-130184Azido-PEG8-NHS ester -
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