m-PEG12-NHS ester
Based on 1 Customer Validation
m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2207596-93-6
- Formula: C30H55NO16
- Molecular Weight:685.75
-
Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
|
PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2207596-93-6
-
Appearance Solid
-
Molecular Weight 685.75
-
Formula C30H55NO16
-
Color White to off-white
-
SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (145.83 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (264 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4583 mL | 7.2913 mL | 14.5826 mL | 36.4564 mL |
| 5 mM | 0.2917 mL | 1.4583 mL | 2.9165 mL | 7.2913 mL | |
| 10 mM | 0.1458 mL | 0.7291 mL | 1.4583 mL | 3.6456 mL | |
| 15 mM | 0.0972 mL | 0.4861 mL | 0.9722 mL | 2.4304 mL | |
| 20 mM | 0.0729 mL | 0.3646 mL | 0.7291 mL | 1.8228 mL | |
| 25 mM | 0.0583 mL | 0.2917 mL | 0.5833 mL | 1.4583 mL | |
| 30 mM | 0.0486 mL | 0.2430 mL | 0.4861 mL | 1.2152 mL | |
| 40 mM | 0.0365 mL | 0.1823 mL | 0.3646 mL | 0.9114 mL | |
| 50 mM | 0.0292 mL | 0.1458 mL | 0.2917 mL | 0.7291 mL | |
| 60 mM | 0.0243 mL | 0.1215 mL | 0.2430 mL | 0.6076 mL | |
| 80 mM | 0.0182 mL | 0.0911 mL | 0.1823 mL | 0.4557 mL | |
| 100 mM | 0.0146 mL | 0.0729 mL | 0.1458 mL | 0.3646 mL |
m-PEG12-NHS ester Related Classifications
HY-141106 Related Classifications
Powered by Bioz