2375740-98-8

CSN5i-3 Chemical Structure
2375740-98-8

Chemical Structure

CSN5i-3

  • CAS No.: 2375740-98-8
  • Formula:C28H29F2N5O2
  • Molecular Weight:505.56

IUPAC Name: 3-(difluoromethyl)-N-(6-((5S,6S)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl)-[1,1'-biphenyl]-3-yl)-1-isopropyl-1H-pyrazole-5-carboxamide

InChIKey: ANNKHJQLDMGQFM-UIOOFZCWSA-N

SMILES: O=C(C1=CC(C(F)F)=NN1C(C)C)NC2=CC(C3=CC=CC=C3)=C([C@@H]4N5C(CCC[C@@H]4O)=CN=C5)C=C2

Biological Activity: CSN5i-3 is a potent, selective and orally available inhibitor of CSN5/Jab1, and inhibits CSN-catalysed Cul1 deneddylation with an IC50 value of 5.8 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-112134 		CSN5i-3 99.95% CSN5i-3 is a potent, selective and orally available inhibitor of CSN5/Jab1, and inhibits CSN-catalysed Cul1 deneddylation with an IC50 value of 5.8 nM.
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