2377679-85-9
2377679-85-9
Chemical Structure
TLR2/9 antagonist 1
- CAS No.: 2377679-85-9
- Formula:C19H18FNO2
- Molecular Weight:311.35
InChIKey: GDSIRENPKAXCKA-ONEGZZNKSA-N
SMILES: O=CC1=C(C(F)=CC(/C=C/C2=CC=C(C=C2)N3CCCC3)=C1)O
Biological Activity: TLR2/9 antagonist 1 (Compound 24) is a reversible covalent TLR2 (IC₅₀ = 0.5 μM (TLR2/TLR6); IC₅₀ = 0.6 μM (TLR2/TLR1)) and TLR9 (IC₅₀ = 0.32 μM) antagonist. TLR2/9 antagonist 1 has no significant effect on other TLR subtypes. TLR2/9 antagonist 1 can be used for studying central nervous system diseases and malignant tumors caused by inflammation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TLR2/9 antagonist 1 | TLR2/9 antagonist 1 (Compound 24) is a reversible covalent TLR2 (IC₅₀ = 0.5 μM (TLR2/TLR6); IC₅₀ = 0.6 μM (TLR2/TLR1)) and TLR9 (IC₅₀ = 0.32 μM) antagonist. TLR2/9 antagonist 1 has no significant effect on other TLR subtypes. TLR2/9 antagonist 1 can be used for studying central nervous system diseases and malignant tumors caused by inflammation. | |||||||||||||||||||||
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