TLR2/9 antagonist 1
TLR2/9 antagonist 1 (Compound 24) is a reversible covalent TLR2 (IC₅₀ = 0.5 μM (TLR2/TLR6); IC₅₀ = 0.6 μM (TLR2/TLR1)) and TLR9 (IC₅₀ = 0.32 μM) antagonist. TLR2/9 antagonist 1 has no significant effect on other TLR subtypes. TLR2/9 antagonist 1 can be used for studying central nervous system diseases and malignant tumors caused by inflammation.
For research use only. We do not sell to patients.
- CAS No.: 2377679-85-9
- Formula: C19H18FNO2
- Molecular Weight:311.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TLR2 0.5 μM (IC50) |
TLR9 0.32 μM (IC50) |
Chemical Information
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CAS No. 2377679-85-9
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Molecular Weight 311.35
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Formula C19H18FNO2
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SMILES
O=CC1=C(C(F)=CC(/C=C/C2=CC=C(C=C2)N3CCCC3)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR2/9 antagonist 1 Related Classifications
HY-180507 Related Classifications
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