24063-71-6
24063-71-6
Chemical Structure
Isocurcumenol
- CAS No.: 24063-71-6
- Formula:C15H22O2
- Molecular Weight:234.33
IUPAC Name: (3S,3aS,6R,8aS)-3-methyl-8-methylene-5-(propan-2-ylidene)octahydro-6H-3a,6-epoxyazulen-6-ol
InChIKey: DEBDFZGNZTYPMF-NZBPQXDJSA-N
SMILES: O[C@@]1(C2)/C(C[C@]3(O1)[C@@H](C)CC[C@@]3([H])C2=C)=C(C)/C
Biological Activity: Isocurcumenol, an estrogen receptor alpha (ERα) inhibitor isolated from Curcuma zedoaria Rhizomes, possesses anti-tumor acticity, with IC50 values of 99.1μg/mL and 178.2 μg/mL in DLA and KB cells, respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isocurcumenol | 99.47% | Isocurcumenol, an estrogen receptor alpha (ERα) inhibitor isolated from Curcuma zedoaria Rhizomes, possesses anti-tumor acticity, with IC50 values of 99.1μg/mL and 178.2 μg/mL in DLA and KB cells, respectively. | ||||||||||||||||||||
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References
- [1]. Lakshmi S, et al. Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. Int J Med Chem. 2011;2011:253962. [Content Brief]
- [2]. Resmi Mustarichiei, et al. In silico study of curcumol, curcumenol, isocurcumenol, and β-sitosterol as potential inhibitors of estrogen receptor alpha of breast cancer. Basic Medical Research. 2014
Keywords
