2408841-19-8
2408841-19-8
Chemical Structure
PKM2-IN-3
- CAS No.: 2408841-19-8
- Formula:C21H22O4
- Molecular Weight:338.40
IUPAC Name: (E)-4-(4-ethylbenzylidene)-6,8-dimethoxy-3,4-dihydrobenzo[b]oxepin-5(2H)-one
InChIKey: BQNYBXFXLMWECE-LFIBNONCSA-N
SMILES: COC1=C2C(OCC/C(C2=O)=C\C3=CC=C(C=C3)CC)=CC(OC)=C1
Biological Activity: PKM2-IN-3 is an inhibitor of PKM2 kinase with an IC50 value of 4.1 μM. PKM2-IN-3 exhibits an anti-neuroinflammatory effect by inhibiting PKM2-mediated glycolysis and NLRP3 activation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PKM2-IN-3 | 99.44% | PKM2-IN-3 is an inhibitor of PKM2 kinase with an IC50 value of 4.1 μM. PKM2-IN-3 exhibits an anti-neuroinflammatory effect by inhibiting PKM2-mediated glycolysis and NLRP3 activation. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.64
HY-N86733-(4-Hydroxybenzylidene)-5-hydroxy-7-methoxychroman-4-one -
Similarity Score 0.62
HY-N17056(E)-Eucomin -
Similarity Score 0.59
HY-N10069Bonducellin -
Similarity Score 0.59
HY-N4003Isobonducellin -
Similarity Score 0.58
HY-187019Nitric oxide production-IN-2 -
Similarity Score 0.58
HY-N18924'-Demethyleucomin -
Similarity Score 0.57
HY-N119388-Methoxybonducellin -
Similarity Score 0.56
HY-101990IMS2186 -
Similarity Score 0.56
HY-N3212Naringenin trimethyl ether -
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