24211-30-1
24211-30-1
Chemical Structure
Farrerol
Synonym(s): (-)-Farrerol
- CAS No.: 24211-30-1
- Formula:C17H16O5
- Molecular Weight:300.31
IUPAC Name: (S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethylchroman-4-one
InChIKey: DYHOLQACRGJEHX-ZDUSSCGKSA-N
SMILES: O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=C(C)C(O)=C(C)C(O)=C13
Biological Activity: Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6].
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Farrerol | 99.98% | Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects. | ||||||||||||||||||||
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Farrerol (Standard) | 98.14% | Farrerol (Standard) is the analytical standard of Farrerol. This product is intended for research and analytical applications. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects. | ||||||||||||||||||||
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References
- [1]. Ran X, et al. Farrerol Ameliorates TNBS-Induced Colonic Inflammation by Inhibiting ERK1/2, JNK1/2, and NF-κB Signaling Pathway. Int J Mol Sci. 2018 Jul 13;19(7). [Content Brief]
- [2]. Cui B, et al. Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line. Biomed Pharmacother. 2019 Jan;109:112-119. [Content Brief]
- [3]. Dai F, et al. Farrerol inhibited angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathway. Phytomedicine. 2016 Jun 15;23(7):686-93. [Content Brief]
- [4]. Li B, et al. Farrerol overcomes the invasiveness of lung squamous cell carcinoma cells by regulating the expression of inducers of epithelial mesenchymal transition. Microb Pathog. 2019 Jun;131:277. [Content Brief]
- [5]. Li Y, et al. Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways. Int Immunopharmacol. 2019 Oct;75:105739. [Content Brief]
- [6]. Wang L, et al. Farrerol Ameliorates APAP-induced Hepatotoxicity via Activation of Nrf2 and Autophagy. Int J Biol Sci. 2019 Jan 29;15(4):788-799. [Content Brief]
Keywords
