2460924-63-2
2460924-63-2
Chemical Structure
Trk-IN-20
- CAS No.: 2460924-63-2
- Formula:C22H18F2N4
- Molecular Weight:376.40
IUPAC Name: (R,E)-N-(1-(3,5-difluorophenyl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-5-amine
InChIKey: ZHOXAGNPCZTRBN-HZRUHFOJSA-N
SMILES: FC1=CC([C@@H](C)NC2=CC3=C(C=C2)NN=C3/C=C/C4=NC=CC=C4)=CC(F)=C1
Biological Activity: Trk-IN-20 is a kind of 3-vinylindazole derivatives. Trk-IN-20 suppresses Trk kinases functions by phosphorylation inhibition of TrkA/B/C with IC50 values of 1.6 nM, 2.9 nM and 2.0 nM, respectively[1].
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Trk-IN-20 | Trk-IN-20 is a kind of 3-vinylindazole derivatives. Trk-IN-20 suppresses Trk kinases functions by phosphorylation inhibition of TrkA/B/C with IC50 values of 1.6 nM, 2.9 nM and 2.0 nM, respectively. | |||||||||||||||||||||
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References
Keywords
