2468065-01-0
2468065-01-0
Chemical Structure
Pro-Dasatinib
- CAS No.: 2468065-01-0
- Formula:C25H29ClN8O2S
- Molecular Weight:541.07
SMILES: O=C([C@@H]1CCCN1)N(CC2)CCN2C3=NC(C)=NC(NC4=NC=C(C(NC5=C(C=CC=C5Cl)C)=O)S4)=C3
Biological Activity: Pro-Dasatinib (compound 2j), an amino acid analog of Dasatinib (HY-10181), is a potent Src/Abl kinase inhibitor. Pro-Dasatinib has antiproliferative activity against K652 leukemia cancer cells with an IC50 of 0.21 nM.
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Pro-Dasatinib | Pro-Dasatinib (compound 2j), an amino acid analog of Dasatinib (HY-10181), is a potent Src/Abl kinase inhibitor. Pro-Dasatinib has antiproliferative activity against K652 leukemia cancer cells with an IC50 of 0.21 nM. | |||||||||||||||||||||
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Keywords
