2561431-77-2
2561431-77-2
Chemical Structure
RIPK1-IN-16
- CAS No.: 2561431-77-2
- Formula:C20H19N5O2S
- Molecular Weight:393.46
InChIKey: IECXSYCNRXFRJS-AWEZNQCLSA-N
SMILES: CN1C2=CC=CC=C2OC[C@H](NC(C3=NNC(CC4=CC=CC=C4)=N3)=O)C1=S
Biological Activity: RIPK1-IN-16 is an orally active and potent inhibitor of RIPK1. RIPK1-IN-16 inhibits excessive inflammation by blocking RIPK1-mediated necroptosis in vivo. RIPK1-IN-16 protects mouse from TNF-induced systemic inflammatory response syndrome and sepsis[1].
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RIPK1-IN-16 | RIPK1-IN-16 is an orally active and potent inhibitor of RIPK1. RIPK1-IN-16 inhibits excessive inflammation by blocking RIPK1-mediated necroptosis in vivo. RIPK1-IN-16 protects mouse from TNF-induced systemic inflammatory response syndrome and sepsis. | |||||||||||||||||||||
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