2565637-94-5

AB25583 Chemical Structure
2565637-94-5

Chemical Structure

AB25583

  • CAS No.: 2565637-94-5
  • Formula:C22H17ClN4O3S
  • Molecular Weight:452.91

InChIKey: NKBJFGOHTSTLNB-UHFFFAOYSA-N

SMILES: ClC1=CC=C(COC2=NN=C(NC(C3=C(C4=CC=CC=C4OC)C=CN=C3)=O)S2)C=C1

Biological Activity: AB25583 is a Polθ helicase (Polθ-hel) small molecule inhibitor, with an IC50 value of 6 nM. AB25583 selectively kills BRCA1/2 deficient cells and works in synergy with Olaparib (HY-10162) in cancer cells carrying pathogenic BRCA1/2 mutations. AB25583 can be used for tumor research[1].

Cat. No. Product Name Purity Description Pricing
HY-162859 		AB25583 99.87% AB25583 is a Polθ helicase (Polθ-hel) small molecule inhibitor, with an IC50 value of 6 nM. AB25583 selectively kills BRCA1/2 deficient cells and works in synergy with Olaparib (HY-10162) in cancer cells carrying pathogenic BRCA1/2 mutations. AB25583 can be used for tumor research.
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