2624-44-4
2624-44-4
Chemical Structure
Ethamsylate
Synonym(s): Etamsylate
- CAS No.: 2624-44-4
- Formula:C10H17NO5S
- Molecular Weight:263.31
IUPAC Name: diethylamine 2,5-dihydroxybenzenesulfonate
InChIKey: HBGOLJKPSFNJSD-UHFFFAOYSA-N
SMILES: O=S(C1=CC(O)=CC=C1O)(O)=O.CCNCC
Biological Activity: Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis.[1][2][3].
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Ethamsylate | 99.49% | Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis.. | ||||||||||||||||||||
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Ethamsylate (Standard) | ≥98% | Ethamsylate (Standard) is the analytical standard of Ethamsylate. This product is intended for research and analytical applications. Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis.. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.64
HY-N0113AHordenine sulfate -
Similarity Score 0.63
HY-D0261Tiron -
Similarity Score 0.63
HY-B08125-Sulfosalicylic acid dihydrate -
Similarity Score 0.62
HY-W765357Glycine-13C2,15N p-Toluenesulfonate -
Similarity Score 0.60
HY-W100403Choline tosylate -
Similarity Score 0.60
HY-W1282222,4'-Dihydroxydiphenyl sulfone -
Similarity Score 0.60
HY-W65408424 Bisphenol S-13C12 -
Similarity Score 0.60
HY-W3995092-Sulfoterephthalic acid -
Similarity Score 0.60
HY-W090309Monosodium 2-sulfoterephthalate -
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References
- [1]. Zawrotniak M, et al. Selected mucolytic, anti-inflammatory and cardiovascular drugs change the ability of neutrophils to form extracellular traps (NETs). Acta Biochim Pol. 2015;62(3):465-73. [Content Brief]
- [2]. Kovács L, et al. Etamsylate as inhibitor of prostaglandin biosynthesis in pregnant human myometrium in vitro. Experientia. 1981 Nov 15;37(11):1182-3. [Content Brief]
- [3]. Albiñana V, et al. Topically Applied Etamsylate: A New Orphan Drug for HHT-Derived Epistaxis (Antiangiogenesis through FGF Pathway Inhibition). TH Open. 2019 Jul 26;3(3):e230-e243. [Content Brief]
