2631005-84-8
Chemical Structure
Cap-dependent endonuclease-IN-9
- CAS No.: 2631005-84-8
- Formula:C29H22F2N4O7S
- Molecular Weight:608.57
IUPAC Name: (1R,2S)-1-((2S,4R)-4-butyl-1-methylpyrrolidine-2-carboxamido)-1-((2R,3R,4S,5R,6R)-5-((hexadecanoyl-d31)oxy)-3,4-dihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propan-2-yl hexadecanoate-d31
InChIKey: RXUYYAAWOMIREX-NOZRDPDXSA-N
SMILES: O=C1N2[C@@H](CC3=C(N=CO3)C2)N([C@H]4C5=CC=C(F)C(F)=C5CSC6=CC=CC=C64)N7C1=C(C(C=C7)=O)OCOC(OC)=O
Biological Activity: Cap-dependent endonuclease-IN-9 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-9 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-9 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent CN112521386A, compound VI-1)[1].
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Cap-dependent endonuclease-IN-9 | Cap-dependent endonuclease-IN-9 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-9 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-9 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent CN112521386A, compound VI-1). | |||||||||||||||||||||
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