2743436-86-2
2743436-86-2
Chemical Structure
CHK-336
- CAS No.: 2743436-86-2
- Formula:C24H20F2N4O4S2
- Molecular Weight:530.57
InChIKey: XAHAUTPHLZAEKK-UHFFFAOYSA-N
SMILES: O=C(C1=CSC(N2N=C(C(CC3=CC=C(S(=O)(N)=O)C(F)=C3)=C2CC4CC4)C5=CC=C(F)C=C5)=N1)O
Biological Activity: CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM). CHK-336 inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CHK-336 | 98.50% | CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM). CHK-336 inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-183858NCATS-SM1440 -
Similarity Score 0.79
HY-176798NCI-006 -
Similarity Score 0.79
HY-151243NCATS-SM1441 -
Similarity Score 0.74
HY-115875LDHA-IN-5 -
Similarity Score 0.73
HY-111108LDH-IN-1 -
Similarity Score 0.49
HY-152261MS6105 -
Similarity Score 0.48
HY-12370TY-51469 -
Similarity Score 0.46
HY-159128hCAIX-IN-21 -
Similarity Score 0.45
HY-171861Nef ligand-1 -
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