275810-55-4
275810-55-4
Chemical Structure
DPC-168
- CAS No.: 275810-55-4
- Formula:C28H36FN3O2
- Molecular Weight:465.60
IUPAC Name: 1-(3-acetylphenyl)-3-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)urea
InChIKey: ASRDPULQBHFPGU-WFIHMLKPSA-N
SMILES: O=C(N[C@H]1[C@H](CN2C[C@H](CC3=CC=C(F)C=C3)CCC2)CCCC1)NC4=CC=CC(C(C)=O)=C4
Biological Activity: DPC-168 is an orally effective CCR3 antagonist (IC50 = 41 nM). DPC-168 exhibits a significant ability to inhibit eosinophil chemotaxis and pulmonary inflammation. DPC-168 can be used for research on airway inflammation[1].
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DPC-168 | DPC-168 is an orally effective CCR3 antagonist (IC50 = 41 nM). DPC-168 exhibits a significant ability to inhibit eosinophil chemotaxis and pulmonary inflammation. DPC-168 can be used for research on airway inflammation. | |||||||||||||||||||||
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