2762619-63-4
2762619-63-4
Chemical Structure
TEAD1/3/4-IN-1
- CAS No.: 2762619-63-4
- Formula:C18H13F4N5O2
- Molecular Weight:407.32
InChIKey: SODJZYMRWMUOMC-UHFFFAOYSA-N
SMILES: O=C(N1CC(C1)N2C(N(C3=NC=CN=C32)C4=CC=C(C(F)(F)F)C=C4)=O)C(F)=C
Biological Activity: TEAD1/3/4-IN-1 is an orally active inhibitor of TEAD1/3/4. TEAD1/3/4-IN-1 inhibits the YAP/TAZ-TEAD interaction, with its EC50 being 2 nM. TEAD1/3/4-IN-1 has anti-proliferative activity against NCI-H226 cells. TEAD1/3/4-IN-1 can be used in the research of lung squamous cell carcinoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TEAD1/3/4-IN-1 | 99.04% | TEAD1/3/4-IN-1 is an orally active inhibitor of TEAD1/3/4. TEAD1/3/4-IN-1 inhibits the YAP/TAZ-TEAD interaction, with its EC50 being 2 nM. TEAD1/3/4-IN-1 has anti-proliferative activity against NCI-H226 cells. TEAD1/3/4-IN-1 can be used in the research of lung squamous cell carcinoma. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
