2763840-83-9
2763840-83-9
Chemical Structure
PARP-1-IN-1
- CAS No.: 2763840-83-9
- Formula:C23H25FN4O
- Molecular Weight:392.47
IUPAC Name: 5-(3-((4-aminopiperidin-1-yl)methyl)phenyl)-8-fluoro-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-1-one
InChIKey: FNXYFOFBZPBUFN-UHFFFAOYSA-N
SMILES: NC1CCN(CC1)CC2=CC(C3=C4CCNC(C5=C4C(N3)=CC(F)=C5)=O)=CC=C2
Biological Activity: PARP-1-IN-1 is a high selective and orally active PARP-1 inhibitor (IC50=0.96 nM). PARP-1-IN-1 has well tolerance and remarkable single dose activity in the MDA-MB-436 xenotransplantation model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PARP-1-IN-1 | PARP-1-IN-1 is a high selective and orally active PARP-1 inhibitor (IC50=0.96 nM). PARP-1-IN-1 has well tolerance and remarkable single dose activity in the MDA-MB-436 xenotransplantation model. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
