2765008-88-4

Atg4B-IN-2 Chemical Structure
2765008-88-4

Chemical Structure

Atg4B-IN-2

  • CAS No.: 2765008-88-4
  • Formula:C21H30O3
  • Molecular Weight:330.46

IUPAC Name: 2,5-bis(4-(10H-phenoxazin-10-yl)phenyl)-1,3,4-thiadiazole

InChIKey: XEPLKXYXNJMMCI-WUKNDPDISA-N

SMILES: O=C(C1=CC=C(C=C1)CCCCCCCCCCC)/C=C/C(O)=O

Biological Activity: Atg4B-IN-2 is a potent competitive Atg4B inhibitor with Ki value of 3.1 μM, also possesses declining PLA2 inhibitory potency, IC50s of 11 μM and 3.5 μM for Atg4B and PLA2, respectively. Atg4B-IN-2 enhances the anticancer activity of anti-castration-resistant prostate cancer agents via autophagy inhibition[1].

Cat. No. Product Name Purity Description Pricing
HY-144636 		Atg4B-IN-2 98.03% Atg4B-IN-2 is a potent competitive Atg4B inhibitor with Ki value of 3.1 μM, also possesses declining PLA2 inhibitory potency, IC50s of 11 μM and 3.5 μM for Atg4B and PLA2, respectively. Atg4B-IN-2 enhances the anticancer activity of anti-castration-resistant prostate cancer agents via autophagy inhibition.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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