2768474-47-9
2768474-47-9
Chemical Structure
Haspin-IN-2
- CAS No.: 2768474-47-9
- Formula:C12H8N4O3
- Molecular Weight:256.22
IUPAC Name: 2-methoxy-10-nitropyrido[3,4-g]quinazoline
InChIKey: WPPGBVWZGMDXKF-UHFFFAOYSA-N
SMILES: COC1=NC2=C(C3=C(C=C2C=N1)C=NC=C3)[N+]([O-])=O
Biological Activity: Haspin-IN-2 (compound 4) is a potent and selective haspin inhibitor with an IC50 of 50 nM. Haspin-IN-1 also inbibits CLK1 and DYRK1A with IC50s of 445 nM and 917 nM, respectively[1].
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Haspin-IN-2 | Haspin-IN-2 (compound 4) is a potent and selective haspin inhibitor with an IC50 of 50 nM. Haspin-IN-1 also inbibits CLK1 and DYRK1A with IC50s of 445 nM and 917 nM, respectively. | |||||||||||||||||||||
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References
Keywords
