2769040-91-5
Chemical Structure
NLRP3-IN-11
- CAS No.: 2769040-91-5
- Formula:C17H17ClN4O2
- Molecular Weight:344.80
IUPAC Name: 5-chloro-2-(4-((2-hydroxy-2-methylpropyl)amino)pyrido[3,4-d]pyridazin-1-yl)phenol
InChIKey: UDNICEVHCYUJFU-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C2=C3C=CN=CC3=C(NCC(C)(C)O)N=N2)C(O)=C1
Biological Activity: NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1].
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NLRP3-IN-11 | 98.79% | NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases. | ||||||||||||||||||||
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Keywords
