2808361-18-2
2808361-18-2
Chemical Structure
Lepodisiran
Synonym(s): LY3819469
- CAS No.: 2808361-18-2
- Formula:N/A
- Molecular Weight:20720.00
SMILES: [Lepodisiran]
Biological Activity: Lepodisiran (LY3819469) is a GalNAc-conjugated small interfering RNA lipid-lowering agent. Lepodisiran targets the hepatic LPA gene and degrades apolipoprotein (a) mRNA to silence its expression, thereby effectively reducing the production of apolipoprotein (a) and serum lipoprotein (a) in a dose-dependent manner. Lepodisiran can be used in studies related to atherosclerotic cardiovascular disease[1].
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Lepodisiran | 91.95% | Lepodisiran (LY3819469) is a GalNAc-conjugated small interfering RNA lipid-lowering agent. Lepodisiran targets the hepatic LPA gene and degrades apolipoprotein (a) mRNA to silence its expression, thereby effectively reducing the production of apolipoprotein (a) and serum lipoprotein (a) in a dose-dependent manner. Lepodisiran can be used in studies related to atherosclerotic cardiovascular disease. | ||||||||||||||||||||
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