2820151-01-5
Chemical Structure
FTI-2153 TFA
- CAS No.: 2820151-01-5
- Formula:C27H31F3N4O5S
- Molecular Weight:580.62
IUPAC Name: methyl (5-((((1H-imidazol-5-yl)methyl)amino)methyl)-2'-methyl-[1,1'-biphenyl]-2-carbonyl)-L-methioninate 2,2,2-trifluoroacetate
InChIKey: LRKNQRCLUQTFRP-BQAIUKQQSA-N
SMILES: CSCC[C@@H](C(OC)=O)NC(C1=CC=C(CNCC2=CN=CN2)C=C1C3=CC=CC=C3C)=O.OC(C(F)(F)F)=O
Biological Activity: FTI-2153 TFA is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 TFA is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FTI-2153 TFA | 99.11% | FTI-2153 TFA is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 TFA is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity. | ||||||||||||||||||||
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Keywords
