2847829-86-9
2847829-86-9
Chemical Structure
PROTAC ER Degrader-16
- CAS No.: 2847829-86-9
- Formula:C47H54BN5O6
- Molecular Weight:795.77
InChIKey: KNJAMZGBBBEBDI-INXUWUOZSA-N
SMILES: CC/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)B(O)O)/C3=CC=C(C=C3)OCCN4CCN(CC4)CC5CCN(CC5)C6=CC7=C(C(N(C7)C8CCC(NC8=O)=O)=O)C=C6
Biological Activity: PROTAC ER Degrader-16 is an orally active ERα PROTAC degrader with a DC50 of 1.4 nM and an IC50 of 1.9 nM. PROTAC ER Degrader-16 inhibits ER-dependent breast cancer cell proliferation and exerts anti-tumor effects in mouse models. PROTAC ER Degrader-16 can be used for breast cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PROTAC ER Degrader-16 | PROTAC ER Degrader-16 is an orally active ERα PROTAC degrader with a DC50 of 1.4 nM and an IC50 of 1.9 nM. PROTAC ER Degrader-16 inhibits ER-dependent breast cancer cell proliferation and exerts anti-tumor effects in mouse models. PROTAC ER Degrader-16 can be used for breast cancer research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
