2863686-81-9
2863686-81-9
Chemical Structure
DRB18
- CAS. Nr.: 2863686-81-9
- Formula:C22H23ClN2O2
- Molecular Weight:382.88
IUPAC Name: 5,5'-(((4-chloro-1,2-phenylene)bis(azanediyl))bis(methylene))bis(2-methylphenol)
InChIKey: WNTAQMQIZGJASL-UHFFFAOYSA-N
SMILES: ClC1=CC(NCC2=CC(O)=C(C)C=C2)=C(NCC3=CC=C(C)C(O)=C3)C=C1
Biological Activity: DRB18 is a potent pan-class GLUT inhibitor. DRB18 alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to G1/S phase arrest and increase oxidative stress and necrotic cell death. DRB18 has anti-tumor activity[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
DRB18 | 99.58% | DRB18 is a potent pan-class GLUT inhibitor. DRB18 alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to G1/S phase arrest and increase oxidative stress and necrotic cell death. DRB18 has anti-tumor activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.54
HY-23206DAN-1 EE hydrochloride -
Similarity Score 0.53
HY-W075646N,N'-(1,4-Phenylenebis(methylene))bis(pyridin-4-amine) -
Similarity Score 0.52
HY-163074Ferroptosis-IN-6 -
Similarity Score 0.52
HY-139177PPARα agonist 2 -
Similarity Score 0.52
HY-148543FC-99 -
Similarity Score 0.52
HY-W072962WX2-43 -
Similarity Score 0.51
HY-15589RGW9508 (Standard) -
Similarity Score 0.51
HY-149820MAO-B-IN-22 -
Similarity Score 0.51
HY-162487HDAC-IN-72 -
Explore the MedChemAI to find more analogs
