2863686-81-9
2863686-81-9
Chemical Structure
DRB18
- CAS No.: 2863686-81-9
- Formula:C22H23ClN2O2
- Molecular Weight:382.88
IUPAC Name: 5,5'-(((4-chloro-1,2-phenylene)bis(azanediyl))bis(methylene))bis(2-methylphenol)
InChIKey: WNTAQMQIZGJASL-UHFFFAOYSA-N
SMILES: ClC1=CC(NCC2=CC(O)=C(C)C=C2)=C(NCC3=CC=C(C)C(O)=C3)C=C1
Biological Activity: DRB18 is a potent pan-class GLUT inhibitor. DRB18 alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to G1/S phase arrest and increase oxidative stress and necrotic cell death. DRB18 has anti-tumor activity[1].
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DRB18 | 99.58% | DRB18 is a potent pan-class GLUT inhibitor. DRB18 alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to G1/S phase arrest and increase oxidative stress and necrotic cell death. DRB18 has anti-tumor activity. | ||||||||||||||||||||
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